Mechanims and possibilities of liposomal gene transfer to affect dermal and epidermal regeneration using the IGF-I cDNA construct Review Article
نویسنده
چکیده
Abbreviations: 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyl ethyl ammonium bromide, (DMRIE); activation protein-1, (AP-1); Basement membranes, (BM); colony stimulating factor (CSF), dioleoylphosphatidyl ethanolamine, (DOPE); fibroblast growth factor, (FGF); growth hormone, (GH); Hepatocyte growth factor, (HGF); insulin-like growth factor-I, (IGF-I); interleukin-1, (IL-1); interleukin-6, (IL-6); interleukin-8, (IL-8); keratinocyte growth factor, (KGF); nuclear factor kappa B, (NF-kB) ; Platelet derived growth factor, (PDGF-α, -β); transforming growth factor-α, (TGF-α); transforming growth factor-β, (TGF-β); tumor necrosis factor-a, (TNF-a); Vascular endothelial growth factor, (VEGF)
منابع مشابه
Exogenous liposomal IGF-I cDNA gene transfer leads to endogenous cellular and physiological responses in an acute wound.
The purpose of the present study was to examine whether exogenous liposomal cDNA gene transfer is recognized by the cell and causes endogenous cellular and physiological responses. When administered as a protein, IGF-I is known to cause adverse side effects due to lack of cellular responses. Therefore, we used IGF-I cDNA as a vector to study cellular and physiological effects after liposomal ad...
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